Figure 6.
Effect of Ab181 on neuronal activity in the TCC. Ab181 effectively inhibited stimulus-evoked neuronal activity in the TCC (A). The maximum inhibition was very similar to the one observed after the intravenous administration of sumatriptan (B). By contrast, an inhibiting effect on spontaneous background activity was not observed (C). Ab181 did not affect arterial blood pressure throughout the entire course of the experiment (D). TCC, trigeminocervical complex.