Table 2.
Association between LDL-C/HDL-C ratio concordance with TC and CIMT risk
| No. of participants/cases | Model 1a (HR (95%CI)) |
Model 2b (HR (95%%CI)) |
Model 3c (HR (95%%CI)) |
|
|---|---|---|---|---|
| Total | ||||
| Concordantly low LDL-C/HDL-C ratio and low TC | 8119/923 | 1 | 1 | 1 |
| Discordantly low LDL-C/HDL-C ratio and high TC | 2060/383 | 1.00 (0.89, 1.13) | 1.04 (0.92, 1.17) | 1.04 (0.92, 1.18) |
| Discordantly high LDL-C/HDL-C ratio and low TC | 1620/269 | 1.59 (1.38, 1.83) | 1.55 (1.34, 1.78) | 1.54 (1.33, 1.77) |
| Concordantly high LDL-C/HDL-C ratio and high TC | 1812/420 | 1.66 (1.47, 1.86) | 1.65 (1.45, 1.87) | 1.64 (1.45, 1.86) |
| Sensitivity analysis by excluding CIMT in the first 2 years | ||||
| Concordantly low LDL-C/HDL-C ratio and low TC | 7915/719 | 1 | 1 | 1 |
| Discordantly low LDL-C/HDL-C ratio and high TC | 2013/336 | 1.06 (0.93, 1.21) | 1.09 (0.95, 1.24) | 1.1 (0.96, 1.25) |
| Discordantly high LDL-C/HDL-C ratio and low TC | 1561/210 | 1.65 (1.41, 1.93) | 1.60 (1.37, 1.89) | 1.60 (1.36, 1.87) |
| Concordantly high LDL-C/HDL-C ratio and high TC | 1720/328 | 1.63 (1.42, 1.86) | 1.61 (1.4, 1.85) | 1.61 (1.40, 1.85) |
aModel 1: adjusted for age, gender at baseline
bModel 2: adjusted for age, gender, BMI, smoking, drinking, WC, TC, TG, creatinine, lipid-lowering medications, T2DM, hypertension, and fatty liver at baseline
cModel 3: adjusted for age, gender, BMI, smoking, drinking, WC, TC, TG, creatinine, WBC, lipid-lowering medications, T2DM, hypertension, and fatty liver at baseline