. 2020 Jun 17;15:57. doi: 10.1186/s13006-020-00301-z

Table 3.

The interrelation between Sirtuin3, 8-hydroxy-2-deoxyguanosine, brain-derived neurotrophic factor and serotonin in early breast milk of mothers giving birth at term vaginally or by Caesarean section and those delivering preterm (Spearman’s rank correlation)

		Vaginal birth at term				Caesarean section at term				Preterm birth
		SIRT3	8-OHdG	BDNF	5-HT	SIRT3	8-OHdG	BDNF	5-HT	SIRT3	8-OHdG	BDNF	5-HT
Biomarkers in breast milk
SIRT3	R		0.41^*	−0.20	0.48^*		0.50^**	0.05	0.40^*		0.40^*	−0.20	0.54^**
SIRT3	p		0.04	0.34	0.01		0.006	0.81	0.03		0.03	0.26	0.001
8-OHdG	R	0.41^*		−0.29	0.78^**	0.50^**		−0.08	0.43^*	0.40^*		−0.26	0.40^*
8-OHdG	p	0.04		0.16	0.000	0.01		0.67	0.02	0.03		0.15	0.02
BDNF	R	−0.20	−0.29		−0.34	0.05	−0.08		−0.17	− 0.20	− 0.26		− 0.26
BDNF	p	0.34	0.16		0.09	0.81	0.67		0.37	0.26	0.15		0.15
5HT	R	0.48^*	0.78^**	−0.34		0.40^*	0.43^*	−0.17		0.54^**	0.40^*	−0.26
5HT	p	0.01	0.000	0.09		0.03	0.02	0.37		0.001	0.02	0.15

SIRT3 Sirtuin 3, 8-OHdG 8-hydroxy-2′-deoxyquanosine, BDNF Brain-derived neurotrophic factor, 5-HT Serotonin

**= p < 0.01, *= p < 0.05