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. 2020 Jun 17;20:66. doi: 10.1186/s12880-020-00467-2

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Examples of the evaluation of lesions´ vascularity using the MVI technique. Histopathologically verified fibroadenoma in a 37-year-old female patient (a, b, c). There is a well-circumscribed hypoechoic mass (a) with heterogenous internal enhancement (b) and with rich vascularization compared to the surrounding tissue (c). Verified invasive carcinoma of no special type (NST) in a 79-year-old female patient (d, e, f). Greyscale ultrasound shows poorly defined hypoechoic mass (d). A post-processed CEUS image using MVI application displays peripheral penetrating vessels (e) and heterogeneous internal perfusion of the malignant tumor (f). Abbreviations: MVI, MicroVascular Imaging; NST, invasive carcinoma of no special type; CEUS, contrast-enhanced ultrasound