(Fig A) CD45 staining, Representative photomicrographs of CD45 positive cells and histograms summarising expression. (Fig B) CD45 glomerular staining, Representative photomicrographs of CD45 positive cells and histograms summarising expression. (Fig C) F4/80 Staining. Representative photomicrographs of immunohistochemistry for tubulointerstitial F4/80 stain for activated macrophages and histograms summarising expression. Control IgG1 staining was performed to confirm specific staining (not shown). Data presented as mean ± SEM with (*p<0.05, **p<0.01 vs control, #p<0.05 vs DM) n = 6–8. Bar = 200μm DM, Diabetes Mellitus; SSAOi, Semicarbazide Sensitive Amine Oxidase Inhibitor; Telmi, telmisartan.