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. 2020 Jun 18;15(6):e0234508. doi: 10.1371/journal.pone.0234508

Table 1. Clinical features and laboratory findings for the 5 patients with neurological manifestations.

Serum analysis CSF analysis
Patient ID Age (yr) /sex Clinical classifi-cation* Date of sample collection (mo-yr) Clinical features WBC (x103/mm) Hematocrit (%) platelet count (x103/mm) WBC (x103/mm) Protein (mg/dl) Glucose (mg/dl) CSF/blood sugar ratio (%)
1 24/M SD Jun-17 fever, muscle and joint pain, pain in eye socket, nausea, headache, vomiting, rash, irritability, lethargy, photophobia, neck stiffness, alternation of mental status, encephalitis 2.7 35.7 47.8 15 67 124 97
(80% neutrophils, 20% lymphocytes)
2 19/F SD Aug-17 flushing, gum bleeding, headache, vomiting, free fluid in abdomen/pelvis, abdominal pain, liver enlargement, photophobia, irritability, confusion, loss of consciousness, respiratory failure, generalized fits, encephalitis 2.3 36.7 37.9 119 92.8 - -
3 17/M SD Jul-17 fever, muscle and joint pain, pain in eye socket, nausea, headache, vomiting, irritability, neck stiffness, alternation of mental status, encephalitis 5.8 27.8 67.7 246 61.7 97.8 86.5
(11% neutrophils, 89% lymphocytes)
4 7/F SD Jun-17 fever, muscle and joint pain, pain in eye socket, nausea, headache, vomiting, irritability, alternation of mental status, encephalitis 3.8 29.9 113.9 42 42.1 132.1 78.9
(83% neutrophils, 17%lymphocytes)
5 10/F SD Nov-17 fever, muscle and joint pain, pain in eye socket, nausea, headache, vomiting, liver enlargement, photophobia, irritability, confusion, alternation of mental status, encephalitis 4.7 36.5 77.9 8 104 78.9 72
(100% lymphocytes)

* Clinical classification according to WHO 2009 criteria.