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Flow chart illustrating the diagnostic criteria used for identifying CSF HIV escape and criteria used for changing ART regimen in patients. AZT = zidovudine, CSF = cerebrospinal fluid, DRM = drug resistance mutations, GRT = genotypic HIV-1 resistance testing, INSTI = integrase inhibitor, NRTI = nucleoside reverse transcriptase inhibitor, PI/r = boosted protease inhibitor.
