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. 2018 Jun 4;29(6):2716–2727. doi: 10.1093/cercor/bhy140

Figure 2.

Figure 2.

Reduced hippocampal oscillatory activity in non-anesthetized TgF344-AD rats. (A) Example of unfiltered traces of hippocampal CA1 LFP from freely-behaving WT and TgF344-AD rats. Significantly reduced power of (B) theta oscillations, (C) sharp-wave ripples (SWRs, 100–250 Hz), and (D) low gamma band (30–50 Hz) during SWRs in TgF344-AD rats compared with their WT controls. (**P < 0.001). Examples of (E) theta oscillation (filtered between 3 Hz and 12 Hz), and (F) SWR (unfiltered) traces; scale bars: 0.5 mV, 1 s for the theta traces; 0.1 mV, 0.1 s for the SWR.