Table 2. Specific toxicity with Palbociclib.
| Specific Toxicity with Palbociclib (n:128 p) | % | |||||
|---|---|---|---|---|---|---|
| n available | No | G1 | G2 | G3 | G4 | |
| Leukopenia | 98 | 14.3 | 57.6 | 31.3 | 6.1 | 8.2 |
| Anaemia | 99 | 57.6 | 31.3 | 6.1 | 4.0 | 1.0 |
| Thrombocytopenia | 99 | 75.8 | 14.1 | 7.1 | 3.0 | 0 |
| Fatigue | 99 | 44.4 | 39.4 | 12.1 | 4.0 | 0 |
| Headache | 98 | 93.9 | 6.1 | 0 | 0 | 0 |
| Alopecia | 76 | 78.9 | 19.0 | 1.3 | - | - |
| Nausea | 99 | 86.9 | 11.1 | 2.0 | 0 | 0 |
| Vomiting | 99 | 94.0 | 4.0 | 2.0 | 0 | 0 |
| Diarrhea | 99 | 84.8 | 7.1 | 6.1 | 2.0 | 0 |
| Constipation | 100 | 90.0 | 7.0 | 3.0 | 0 | 0 |
| Hot flushes | 99 | 91.9 | 4.0 | 3.0 | 1.0 | 0 |
| Arthralgia | 99 | 69.7 | 25.3 | 4.0 | 1.0 | 0 |
| Cough | 97 | 93.8 | 5.2 | 1.0 | 0 | 0 |
| Decreased appetite | 98 | 91.8 | 8.2 | 0 | 0 | 0 |
| Stomatitis | 98 | 93.9 | 4.1 | 2.0 | 0 | 0 |
| Mucositis | 99 | 97.0 | 2.0 | 1.0 | 0 | 0 |
| Dizziness | 99 | 92.9 | 5.1 | 1.0 | 1.0 | 0 |
| Abdominal pain | 95 | 93.7 | 6.3 | 0 | 0 | 0 |
| Pyrexia | 94 | 95.7 | 4.3 | 0 | 0 | 0 |
| Pruritus | 92 | 95.7 | 4.3 | 0 | 0 | 0 |
| Others * | 88 | 91.0 | 9.0 | |||
*
Pulmonary embolism 1 p; xerostomy 1 p; cutaneous rash G1: 1 p, G2: 1 p; hyperglycemia G2: 1 p; femoral head osteonecrosis: 1 p; acute blepharitis G1: 1p; hand-foot syndrome G1: 1p.