Figure 1. Percentages of CD4⁺ T-cells in GIT, FRT and WB.

CD4⁺ T-cell percentage, relative to all viable CD3⁺ cells, is indicated on the y-axis. Tissue types are indicated on the x-axis. After initial gating based on scatter characteristics and doublet discrimination, viable cells (based on Aqua dye exclusion) were gated for expression of CD3, followed by CD4⁹. As described in the text, the No cART group included two HIV controllers; data points for these two participants are identified as red squares with black circles. Abbreviations: Endo, endometrium; Uninf, uninfected; WB, whole blood. Comparisons between groups and tissues were performed with Mann-Whitney and Wilcoxon matched pairs signed rank tests, respectively. Horizontal and vertical bars represent mean and standard deviation, respectively. Significant differences, either between participant groups within a single tissue type or between tissues within a participant group, are indicated by horizontal brackets.