. Author manuscript; available in PMC: 2020 Jul 1.

Published in final edited form as: Gastrointest Endosc Clin N Am. 2020 Apr 14;30(3):597–609. doi: 10.1016/j.giec.2020.02.015

Table 2.

Level of risk for family member of patients with advanced colorectal polyps

	Risk in FDR, OR/RR (95% CI)
Pathology in Proband	AA	CRC
Advanced Adenoma	6.05 (2.74–13.36)^39,a	—
Tubular adenoma ≥10 mm	8.59 (3.4–21.45)³⁹	3.9 (0.89–17.01)⁴⁰
	2.27 (1.01–5.09)^40,b
Adenoma with villous histology	1.65 (1.28–2.14)^37,c	1.68 (1.29–2.18)³⁷
	6.28 (2.02–19.53)³⁹
Adenoma with high-grade dysplasia	19.98 (2.03–1.97)³⁹	—

In siblings.

For composite endpoint of large adenoma and/or CRC.

For adenoma with villous histology only (not advanced by size or high-grade dysplasia).