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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Bioorg Chem. 2020 May 15;100:103934. doi: 10.1016/j.bioorg.2020.103934

Table 1. Cytotoxic concentration 50% (CC50) of compounds P8, P9, P10, P12, P19, and P25 in leukemic cell lines (CEM, K562 and KCL22).

Cells were exposed to different concentrations of compounds for 48 h.

Compound Cell Line CC50 (μM)
P8 CEM 36.9±1.11
K562 40.28% cell death at 100 μM
KCL22 29.22% cell death at 100 μM
P9 CEM 4.80% cell death at 100 μM
K562 101.8±2.45
KCL22 6.54% cell death at 100 μM
P10 CEM 2.39% cell death at 100 μM
K562 27.06% cell death at 100 μM
KCL22 17.4±2.4
P12 CEM 38.67% cell death at 100 μM
K562 39.42% cell death at 100 μM
KCL22 24.81% cell death at 100 μM
P19 CEM 79.9±3.74
K562 85.4±3.25
KCL22 43.2±0.23
P25 CEM 39±1.69
K562 65.6±1.13
KCL22 82.2±0.32