Table 1. Cytotoxic concentration 50% (CC50) of compounds P8, P9, P10, P12, P19, and P25 in leukemic cell lines (CEM, K562 and KCL22).
Compound | Cell Line | CC50 (μM) |
---|---|---|
P8 | CEM | 36.9±1.11 |
K562 | 40.28% cell death at 100 μM | |
KCL22 | 29.22% cell death at 100 μM | |
P9 | CEM | 4.80% cell death at 100 μM |
K562 | 101.8±2.45 | |
KCL22 | 6.54% cell death at 100 μM | |
P10 | CEM | 2.39% cell death at 100 μM |
K562 | 27.06% cell death at 100 μM | |
KCL22 | 17.4±2.4 | |
P12 | CEM | 38.67% cell death at 100 μM |
K562 | 39.42% cell death at 100 μM | |
KCL22 | 24.81% cell death at 100 μM | |
P19 | CEM | 79.9±3.74 |
K562 | 85.4±3.25 | |
KCL22 | 43.2±0.23 | |
P25 | CEM | 39±1.69 |
K562 | 65.6±1.13 | |
KCL22 | 82.2±0.32 |