Table 2.
1st hour | 2nd hour | 3rd hour | |||||||
---|---|---|---|---|---|---|---|---|---|
Treatment | Activity/1000 | Mins rest | # rest periods | Activity/1000 | Mins rest | # rest periods | Activity/1000 | Mins rest | # rest periods |
Saline | 3.8 ±1.1 | 0.0 ± 0 | 0.0 ± 0 | 2.5 ± 2.2 | 4.3 ±5.7 | 0.4 ± 0.5 | 1.4 ± 1.6 | 11.1 ± 9.4 | 1.4 ± 1.1 |
12.5 mg L-dopa | 1.6 ±1.1**** | 7.7 ± 8.3 * | 1.0 ± 1.0 * | 1.9 ± 1.2 | 3.4 ± 4.7 | 0.6 ± 0.8 | 1.7 ±1.5 | 12.0 ± 9.8 | 1.0 ± 0.8 |
25.0 mg L-dopa | 1.5 ± 1.0*** | 3.4 ±4.7* | 0.4 ± 0.5* | 0.6 ± 0.2* | 6.0 ± 10.0 | 0.6 ± 1.0 | 0.9 ± 0.7 | 10.3 ± 8.3 | 1.3 ± 0.8 |
0.5 mg Quin | 1.2 ± 0.8**** | 18.9 ± 16.0** | 1.6 ± 1.1*** | 1.6 ±1.2 | 12.0 ± 9.8 | 1.4 ± 1.0* | 1.7 ± 1.2 | 9.4 ± 12.0 | 0.7 ± 1.0 |
1.0 mg Quin | 0.9 ± 0.7**** | 18.9 ± 15.3** | 1.6 ± 1.1** | 0.5 ± 0.2* | 16.3 ± 9.6* | 1.7 ± 1.0* | 1.0 ± 0.5 | 11.1 ± 4.1 | 1.3 ± 0.5 |
Significance for within subject t test compared to saline
p<0.001
p< 0.005
p< 0.01
p< 0.05
Activity counts: Sum for each animal of number of gross body movements in each 6-minute period detected by the G2 E-Mitter telemetry. Average and SD total activity determined for 6 animals on iron-sufficient diet and 7 on iron-deficient diet.