Extended Data Fig. 3. IGV visualization of the splice donor variant GRCh37:12-40626187-T-C in the GTEx LRRK2 pLoF carrier exome sequencing data and lung tissue RNA-seq data compared to a control GTEx lung RNA-seq sample.

The pLoF variant is observed on reads containing an anchoring missense variant, GRCh37:12-40626185-A-G (A green and G orange), and these reads are presenting normal splicing as seen in the control RNA-seq sample.