Table 3.
Allocation of rats to exposure groups
| Group | Nicotine (µg/L) | Flavor level | OECD | OECD Plus | |||
|---|---|---|---|---|---|---|---|
| Number of male rats | Number of female rats | Number of male rats | Number of female rats | ||||
| PBS | NA | NA | 10 | 10 | 0 | 0 | |
| PG/VG + Nic | 23 | NA | 10 | 10 | 8 | 8 | |
| PG/VG + F-Med | NA | Medium | 10 | 10 | 8 | 8 | |
| PG/VG + Nic + F-Low | 23 | Low | 10 | 10 | 8 | 8 | |
| PG/VG + Nic + F-Med | 23 | Medium | 10 | 10 | 8 | 8 | |
| PG/VG + Nic + F-High | 23 | High | 10 | 10 | 8 | 8 | |
| PG/VG + Nic (R) a | 23 | NA | 8 | 8 | 0 | 0 | |
| PG/VG + Nic + F-High (R) a | 23 | High | 8 | 8 | 0 | 0 | |
| Total | 76 | 76 | 48 | 48 | |||
a (R) Post-exposure (“recovery”) groups