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. 2020 Jun 18;10:9908. doi: 10.1038/s41598-020-66958-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Three line graphs, in participants aged 25, 42 and 73 years old, to demonstrate the three blood flow kinetic energy peaks during the cardiac cycle during diastole and systole. The yellow dot shows the systolic peak of the kinetic energy curve. The blue dot denotes the E-wave peak of the kinetic energy curve. The purple dot is on top of the A-wave peak of the kinetic energy curve. The systolic peak decreases as age increases. Regarding diastole, early tricuspid inflow blood flow kinetic energy sharply decreases, and there is no significant pattern to late tricuspid filling. At age 73 it can be seen that the time for diastole is much longer, this is a compensatory mechanism to allow more time for the ventricle to fill as the kinetic energy of the blood flow is not very high. The x-axis gives the time through the cardiac cycle. The y-axis shows the kinetic energy, in µJ/ml.