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. 2020 Jun 18;10:9907. doi: 10.1038/s41598-020-66735-x

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Differentially expressed genes (DEGs) in patient groups. (A) DEGs in KC. (B) DEGs in KJ. Among successfully tested genes, 8,762 and 8,990 genes have log₂ (fold change) between −8 and 8 in KC and KJ, respectively. Down-regulated genes (q value ≤ 0.01, and fold change ≤−2, and FPKM ≥5 in control or patient groups) are labeled in blue; up-regulated genes (q value ≤ 0.01, and fold change ≥2, and FPKM ≥5 in control or patient groups) are labeled in red; genes not significantly changed are in grey.