TABLE 1.
ARID5B SNPs with ALL susceptibility among different ethnic groups.
| SNP | ALL subtype | Population characteristics | OR | 95% CI | Cases | Controls | P value | Study type | Country | PMID | References |
| rs10821936 | Overall | European | 1.91 | 1.60–2.20 | 317 | 17958 | 1.40 × 10–15 | GWAS | United States | 19684603 | Treviño et al., 2009 |
| rs10821936 | B-hyperdiploid ALL | European | 2.17 | 1.50–3.10 | 124 | 17958 | 1.62 × 10–5 | GWAS | United States | 19684603 | Treviño et al., 2009 |
| rs10821936 | Overall | European American | 1.88 | 1.68–2.10 | 972 | 1386 | 6.9 × 10–30 | GWAS | United States | 23512250 | Xu et al., 2013 |
| rs10821936 | Overall | African American | 1.52 | 1.14–2.02 | 89 | 1363 | 0.004 | GWAS | United States | 23512250 | Xu et al., 2013 |
| rs10821936 | Overall | Hispanic American | 1.95 | 1.60–2.38 | 305 | 1008 | 3.78 × 10–11 | GWAS | United States | 23512250 | Xu et al., 2013 |
| rs10821936 | Overall | Multi-ethnics | 1.86 | 1.71–2.03 | 1605 | 6661 | 5.88 × 10–46 | GWAS | United States | 23512250 | Xu et al., 2013 |
| rs10821936 | Overall | Whites | 2.13 | 1.77–2.58 | 978 | 1046 | 2.19 × 10–15 | Candidate gene | China | 22291082 | Xu et al., 2012 |
| rs10821936 | Overall | Hispanics | 1.92 | 1.50–2.45 | 330 | 541 | 2.14 × 10–7 | Candidate gene | China | 22291082 | Xu et al., 2012 |
| rs10821936 | Overall | Blacks | 2.09 | 1.31–3.30 | 93 | 112 | 0.0015 | GWAS | United States | 20054350 | Yang et al., 2010 |
| rs10821936 | Overall | Non-Hispanic Whites | 1.91 | 1.60–2.20 | 317 | 17958 | 1.40 × 10–15 | GWAS | United States | 20054350 | Yang et al., 2010 |
| rs10821936 | B-hyperdiploid ALL | Blacks | 6.62 | 2.02–21.90 | 16 | 112 | 0.0021 | GWAS | United States | 20054350 | Yang et al., 2010 |
| rs10821936 | B-hyperdiploid ALL | Non-Hispanic Whites | 4.63 | 1.67–2.82 | 108 | 17958 | 1.30 × 10–10 | GWAS | United States | 20054350 | Yang et al., 2010 |
| rs10821936 | ETV6-RUNX1 ALL | Blacks | 2.01 | 0.82–4.96 | 23 | 112 | 0.13 | GWAS | United States | 20054350 | Yang et al., 2010 |
| rs10821936 | ETV6-RUNX1 ALL | Non-Hispanic Whites | 1.78 | 0.92–3.64 | 45 | 17958 | 0.09 | GWAS | United States | 20054350 | Yang et al., 2010 |
| rs10821936 | Overall | Chinese | 1.81 | 1.42–2.30 | – | – | <0.0001 | Candidate gene | China | 23608171 | Wang et al., 2013 |
| rs10821936 | B-cell ALL | Latvian population | 1.67 | 1.10–2.67 | – | – | 0.028 | Candidate gene | Latvia | 27279837 | Prasad et al., 2010 |
| rs10821936 | Overall | Hungarian | 1.43 | 1.20–1.71 | 543 | 529 | 7.31 × 10–5 | Candidate gene | Hungary | 23021489 | Lautner-Csorba et al., 2012 |
| rs10821936 | B-cell ALL | Hungarian | 1.53 | 1.26–1.85 | 390 | 529 | 1.95 × 10–5 | Candidate gene | Hungary | 23021489 | Lautner-Csorba et al., 2012 |
| rs10821936 | B-cell ALL | European | 2.18 | 1.48–3.20 | 129 | 99 | 1.70 × 10–7 | Candidate gene | Canada | 20460642 | Healy et al., 2010 |
| rs10821936 | B-cell ALL | Indian | 0.67 | 0.47–0.94 | 162 | 150 | 0.019 | Candidate gene | India | 27644650 | Bhandari et al., 2016 |
| rs10821936 | Overall | Multi-ethnics | 2.57 | 1.74–3.79 | 160 | 43 | 9 × 10–7 | Candidate gene | United States | 23692655 | Linabery et al., 2013 |
| rs10821936 | B-hyperdiploid ALL | Multi-ethnics | 8.42 | 4.11–17.25 | 30 | 43 | 1 × 10–9 | Candidate gene | United States | 23692655 | Linabery et al., 2013 |
| rs10821936 | B-cell ALL | Spanish | 1.84 | 1.23–2.75 | 219 | 397 | 4.5 × 10–7 | Candidate gene | Spain | 24013273 | Gutierrez-Camino et al., 2013 |
| rs10821936 | MLL-germline ALL | Non-hispanic Europeans | 7.20 | 2.50–20.60 | 11 | 43 | 0.0002 | Candidate gene | United States | 22422485 | Ross et al., 2013 |
| rs10821936 | MLL-germline ALL | Whites and Non-whites | 2.77 | 1.40–5.47 | 45 | 273 | – | Candidate gene | Spain | 24564228 | Emerenciano et al., 2014 |
| rs10821936 | MLL-r ALL | Whites and Non-whites | 3.04 | 1.61–4.72 | 67 | 273 | – | Candidate gene | Spain | 24564228 | Emerenciano et al., 2014 |
| rs7089424 | Overall | European | 1.65 | 1.54–1.76 | 907 | 2,398 | 6.70 × 10–19 | GWAS | United Kingdom | 19684604 | Papaemmanuil et al., 2009 |
| rs7089424 | Overall | Tunisian population | 0.49 | 0.31–0.79 | 58 | 150 | 0.0022 | Candidate gene | Thailand | 27184773 | Gharbi et al., 2016 |
| rs7089424 | Overall | Mexican | 2.00 | 1.60–2.50 | 285 | 476 | – | Candidate gene | Mexico | 28476190 | Bekker-Mendez et al., 2016 |
| rs7089424 | Overall | Yemeni | 2.19 | 1.08–4.45 | 136 | 153 | 0.02 | Candidate gene | Malaysia | 28381164 | Al-Absi et al., 2017 |
| rs7089424 | Overall | Hispanics | 1.98 | 1.59–2.48 | 300 | 406 | 1 × 10–9 | Candidate gene | United States | 23836053 | Chokkalingam et al., 2013 |
| rs7089424 | Overall | Non-hispanic Whites | 1.84 | 1.43–2.37 | 225 | 369 | 2.2 × 10–6 | Candidate gene | United States | 23836053 | Chokkalingam et al., 2013 |
| rs7089424 | Overall | Polish | 1.94 | 1.26–3.00 | 398 | 731 | 0.003 | Candidate gene | Poland | 21889209 | Pastorczak et al., 2011 |
| rs7089424 | Precursor B-cell ALL | European | 1.80 | 1.62–2.00 | 1384 | 1877 | 5.9 × 10–28 | Candidate gene | Germany | 20042726 | Prasad et al., 2010 |
| rs10994982 | B-hyperdiploid ALL | European | 1.72 | 1.20–2.40 | 0.003 | GWAS | United States | 19684603 | Treviño et al., 2009 | ||
| rs10994982 | MLL-germline ALL | Whites and Non-whites | 2.97 | 1.08–8.12 | 34 | 377 | – | Candidate gene | Spain | 24564228 | Emerenciano et al., 2014 |
| rs10994982 | MLL-r ALL | Whites and Non-whites | 1.50 | 0.70–3.22 | 72 | 377 | – | Candidate gene | Spain | 24564228 | Emerenciano et al., 2014 |
| rs10821938 | Precursor B-cell ALL | Thai population | 0.73 | 0.55–0.97 | 190 | 182 | 0.03 | Candidate gene | Thailand | 20919861 | Vijayakrishnan et al., 2010 |