Table 1.
Specific and non-specific in vitro effects of artemisone.
Cells | Artemisone ED50 | Artesunate ED50 |
---|---|---|
P. falciparum | 1–3 ng/ml | 8–12 ng/ml |
S. epidermidis | Above 5 µg/ml | Above 5 µg/ml |
E. coli 8957 | Above 5 µg/ml | Above 5 µg/ml |
THP-1 human monocytes | 174 µg/ml | 67 µg/ml |
HT-29 human colon cells | Above 100 µg/ml | 70 µg/ml |