Figure 1.

Effect of PR-957 on Ang II–upregulated proteasome subunit expressions and their corresponding proteasome activity. (A) The structure of PR-957. (B) Changes of proteasome activities in the LV tissues of Ang II–infused mice in the presence or absence of PR-957 for 2 weeks (n = 5). (C) Representative images of proteasome subunit expressions and the quantification of each protein band (n = 5). Data are expressed as mean ± SEM, and n represents the number of animals per group. *P < 0.05, **P < 0.01 vs. saline; ^#P < 0.05 vs. Ang II.