Table 1.

Echocardiographic Analysis in wild type mice after Ang II infusion and PR-957 treatment.

Parameter	Saline	PR-957	Ang II	AngII+PR-957
HR(bpm)	545 ± 3.5	538 ± 4.8	536 ± 6.7	544 ± 4.7
LV Mass(AW)(mg)	83.59 ± 3.86	84.45 ± 10.33	97.35 ± 6.36*	82.18 ± 4.46#
LVID;d(mm)	4.11 ± 0.08	4.08 ± 0.2	4.17 ± 0.04*	3.97 ± 0.1
LVID;s(mm)	2.64 ± 0.09	2.66 ± 0.15	2.37 ± 0.05*	2.75 ± 0.12
LVPW;d(mm)	0.68 ± 0.03	0.72 ± 0.03	0.98 ± 0.07*	0.65 ± 0.01#
LVPW;s(mm)	1.05 ± 0.04	1.05 ± 0.01	1.25 ± 0.08*	0.94 ± 0.05#
LVAW;d(mm)	0.63 ± 0.02	0.68 ± 0.03	0.81 ± 0.02*	0.61 ± 0.03#
LVAW;s(mm)	0.87 ± 0.02	0.85 ± 0.04	1.12 ± 0.05*	0.81 ± 0.04#
FS(%)	25.29 ± 0.22	26.33 ± 2.15	28.37 ± 3.31	24.55 ± 1.46

Values are mean ± SEM, n(%).

HR, heart rate; LV Mass, left ventricular mass; LVID, left ventricular internal diameter; LVPW, left ventricular posterior wall; LVAW, anterior left ventricular wall. *P < 0.05 vs Saline; ^#P < 0.05 vs Ang II.