Table 2.
Echocardiographic Analysis in Ang II-infused mice after PR-957 and VO-Ohpic treatment.
| Parameter | Ang II | AngII+PR-957 | AngII+PR-957+VO-Ophpic |
|---|---|---|---|
| HR(bpm) | 525 ± 12.5 | 544 ± 4.7 | 537 ± 15.8 |
| LV Mass(AW)(mg) | 108.7 ± 9.3 | 82.18 ± 4.46* | 91.04 ± 3.51# |
| LVID;d(mm) | 4.36 ± 0.13 | 4.17 ± 0.1 | 4.18 ± 0.05 |
| LVID;s(mm) | 3.2 ± 0.15 | 2.85 ± 0.12 | 2.94 ± 0.1 |
| LVPW;d(mm) | 0.85 ± 0.05 | 0.65 ± 0.01* | 0.78 ± 0.01# |
| LVPW;s(mm) | 1.15 ± 0.06 | 0.84 ± 0.05* | 0.95 ± 0.03# |
| LVAW;d(mm) | 0.86 ± 0.04 | 0.61 ± 0.03* | 0.74 ± 0.03# |
| LVAW;s(mm) | 1.11 ± 0.04 | 0.81 ± 0.04* | 0.95 ± 0.04# |
| FS(%) | 27.47 ± 4.11 | 24.54 ± 1.95 | 26.66 ± 1.87 |
Values are mean ± SEM, n(%).
HR, heart rate; LV Mass, left ventricular mass; LVID, left ventricular internal diameter; LVPD, left ventricular posterior wall; LVAW, anterior left ventricular wall. *P < 0.05 vs Saline; #P < 0.05 vs Ang II+PR-957.