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. 2020 Jun 12;11:901. doi: 10.3389/fmicb.2020.00901

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Copyright © 2020 Ferreira, Tesla, Horácio, Nahum, Brindley, de Oliveira Mendes and Murdock.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of temperature on the expression profile of Zika-exposed Aedes aegypti. (A) Principal Component Analysis (PCA) plot showing the global gene expression profiles. (B) Venn Diagram reporting the number of specific and shared genes. (C) Heatmap plot showing local differences (naming scheme: TC20R1 = replicate 1 for the temperature 20°C). (D) Volcano plot representing the differential gene expression in RNAseq samples from infected Ae. aegypti exposed to three different constant temperatures (20, 28, and 36°C) at 48 h.