Figure 4. The expression of miR-205 was up-regulated in keloid tissues and keloid fibroblasts and miR-205 expression was down-regulated by CACNA1G-AS1.
(A,B) QRT-PCR was carried out to detect the expression of miR-205 in normal skin tissues (NKT), keloid tissues (KT), normal fibroblasts (NF), and keloid fibroblasts (KF). (C) Correlation analysis between CACNA1G-AS1 and miR-205 expression in keloid fibroblasts was performed by Pearson analysis. (D) The expression of miR-205 was measured by qRT-PCR in keloid fibroblasts transfected with pcDNA, CACNA1G-AS1, si-NC, or si-CACNA1G-AS1. ***P<0.001.