Keloid fibroblasts were transfected with miR-NC, miR-205, anti-miR-NC, or anti-miR-205, respectively. (A) The expression level of miR-205 in transfected keloid fibroblasts was detected by qRT-PCR assay. (B) CCK-8 assay was used to evaluate the proliferation of transfected keloid fibroblasts. (C) The invasion of transfected keloid fibroblasts was measured by transwell assay. (D) Flow cytometry was used to assess apoptosis of transfected keloid fibroblasts. (E) The activity of caspase-3 in transfected keloid fibroblasts was examined by Caspase-3 activity assay. **P<0.01, ***P<0.001.