Fig. 3.

Shape deformations in C9 positive ALS in comparison to healthy controls (1), C9 negative ALS compared to healthy controls (2), C9 positive ALS compared to C9 negative ALS (3), PLS compared to C9 negative ALS (4), and PLS patients in contrast to healthy controls (5). Average thalamic mesh is shown in blue and surface projected patterns of atrophy are shown in orange colour at p < 0.05 corrected for age, gender, education, and TIV. Anterior, superior lateral from the right, superior lateral from the left and posterior inferior views are presented. Rt – right, Lt. – left. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)