. 2020 May 21;128(6):1617–1625. doi: 10.1152/japplphysiol.00251.2020

Table 2.

Mixed-effects models for static end-expiratory and end-inspiratory chest wall pressures in supine and prone positions

Pressure	End-Expiratory Pressures				End-Inspiratory Pressures
	Supine		Prone		Supine		Prone
	Coefficient	P value	Coefficient	P value	Coefficient	P value	Coefficient	P value
Pes at PEEP 20 (reference)^*	15 (13;18)	<0.0001^*	14 (12;16)	<0.0001^*	18 (16;21)	<0.0001^*	18 (16;20)	<0.0001^*
Change with PplD	−4 (−5;−2)	<0.0001^*	−4 (−5;−2)	<0.0001^*	−4 (−6;−2)	<0.0001^*	−3 (−5;−2)	<0.0001^*
Change with PplV	−8 (−10;−7)	<0.0001^*	−3 (−4;−2)	<0.0001^*	−9 (−10;-7)	<0.0001^*	−3 (−4;−1)	<0.0001^*
Change with PEEP 15	−2 (−4;0)	0.06^*	−2 (−4;0)	0.02^*	−2 (−4;0)	0.07^*	−3 (−5;−2)	<0.0001^*
Change with PEEP 10	−5 (−7;−3)	<0.0001^*	−5 (−7;−4)	<0.0001^*	−5 (−7;−3)	<0.0001^*	−7 (−8;−5)	<0.0001^*
Change with PEEP 5	−7 (−8;−5)	<0.0001^*	−8 (−9;−6)	<0.0001^*	−6 (−8;−4)	<0.0001^*	−9 (−10;−7)	<0.0001^*
Fixed-effect PEEP^**		<0.0001		<0.0001		<0.0001		<0.0001
PEEP 15 vs. 20		0.69^†		0.26^†		0.74^†		0.02^†
PEEP 10 vs. 20		0.03^†		<0.0001^†		0.0475^†		<0.00001^†
PEEP 5 vs. 20		0.0004^†		<0.0001^†		0.003^†		<0.00001^†
Fixed-effect pressure measurement site^**		<0.0001		<0.0001		<0.0001		<0.0001
PplD vs. Pes		0.011^†		0.009^†		0.006^†		0.045^†
PplV vs. Pes		<0.0001^†		0.04^†		0.0001^†		0.11^†

PEEP, positive end-expiratory pressure; Pes, esophageal pressure; PplD, dorsal pleural pressure; PplV, ventral pleural pressure.

P values for the test of the coefficients vs. 0;

^**

P values for the fixed effects with ANOVA;

^†

comparisons to the reference (PEEP 20 for the fixed-effect PEEP and Pes for the fixed-effect site of measurement) with Dunnett’s test.