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. 2020 Jun 12;11:556. doi: 10.3389/fphys.2020.00556

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Copyright © 2020 Nielsen, Frandsen, Jensen, Prokhorova, Dalgaard, Bech, Nygaard, Suetta and Aagaard.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Protein expression related to angiogenesis signaling at baseline (Pre), 8 days into the training intervention (Mid8), and 3 and 10 days after cessation of training (Post3 and Post10, respectively). Dark gray bars denotes blood flow-restricted group. (A) Vascular endothelial growth factor A (VEGF-A), (B) VEGF-D, (C) VEGF receptor 2 (VEGF-R2), (D) VEGF-R3, (E) angiopoietin-1 (ANGPT1), (F) ANGPT2, and (G) urokinase-type plasminogen activator receptor (uPAR). Pre to Mid/post differences: ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001. Values are means ± SD; BFR: n = 10 at Mid8 n = 9.