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Top 20 nodes with higher degree in transcription factor–target regulatory network.
| Node name | Regulation | Degree | TF |
| HSPA8 | Up | 46 | SIX6 |
| SKP1 | Up | 38 | SIX6 |
| HSPA9 | Up | 36 | SRF |
| FBXO32 | Up | 31 | SRF |
| UBE3A | Up | 28 | SRF |
| FBXW11 | Up | 27 | SRF |
| VDAC1 | Up | 26 | SRF |
| UBE2D3 | Up | 26 | SRF |
| SIAH2 | Up | 26 | SRF |
| ZBTB16 | Up | 25 | SIX6 |
| UBE2H | Up | 24 | SRF |
| HIF1A | Down | 23 | SRF |
| UQCRC2 | Up | 23 | SIX6 |
| MDH2 | Up | 23 | SRF |
| SQSTM1 | Up | 23 | SIX6 |
| FBXO22 | Up | 23 | SRF |
| ASB11 | Up | 23 | NELFA |
| HUWE1 | Up | 22 | SIX6 |
| HECW2 | Up | 22 | SRF |
| RAB1A | Up | 21 | SIX6 |
TF, transcription factor.
