Figure 8. The major components and effects of the respiratory muscle metaboreflex.

Discusses the important findings by [62], who demonstrated that the respiratory muscle-limb reflex has the ability, at least under resting conditions, to reduce significantly limb blood flow and vascular conductance. Furthermore, the results of previous observations [63] provide compelling evidence for the existence of a metaboreflex, with its origin in the respiratory muscles, which can modulate limb perfusion via stimulation of sympathetic nervous system vasoconstrictor neurones.Reproduced with permission from [32].