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. 2020 Jun 19;13:318. doi: 10.1186/s13071-020-04186-z

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 7 — Fold regulation (qPCR) in M1 and M2 cytokine gene expression induced by T. pisiformis cysticercus exosome-like vesicles in RAW264.7 macrophages. LPS and IL-4 served as positive controls for M1 phenotype and M2 phenotype molecules, respectively. PBS served as the negative control for cytokine stimulaton. a, b, g Induction of M1 markers in RAW264.7 macrophages treated with T. pisiformis cysticercus exosome-like vesicles. c-f, h Induction of M2 markers in RAW264.7 macrophages by T. pisiformis cysticercus exosome-like vesicles. Data for the final analysis are from three independent experiments and are expressed as the mean ± standard error (SE). *P < 0.05, **P < 0.01 and ***P < 0.001 were considered statistically significant compared to PBS-treated RAW264.7 macrophages. ^#P <  0.05, ^##P < 0.01 and ^###P < 0.001 were considered statistically significant compared to LPS/IL-4 treated RAW264.7 macrophages (Additional file 5: Table S9)