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. 2020 Jun 14;26(22):3098–3109. doi: 10.3748/wjg.v26.i22.3098

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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Diversity of the gut microbiome at the operational taxonomic unit level. A: Box plot of Shannon and Simpson index. For Shannon index, IL10RA vs healthy control (HC) group, P = 0.0007; Crohn's disease (CD) group vs HC, P = 0.0020. For Simpson index, IL10RA vs HC, P = 0.0008; CD vs HC, P = 0.0040. ^bP < 0.001, ^dP < 0.0001; B: PCoA using unweighted unifrac distance of operational taxonomic unit community structure. R = 0.2750, P = 0.0011. IL10RA: IL10RA group; CD: Crohn's disease group; HC: Healthy control group.