Table 3.
Univariate/multivariate logistic regression results
| Univariate logistic regression | OR (95%CI) | P value | |
| GRS | 1.23 (1.13-1.34) | < 0.0001 | |
| Multivariate logistic regression | OR (95%CI) | P value | |
| GRS | 1.36 (1.06-1.74) | 0.015 | |
| Age at diagnosis/enrollment | 1.14 (1.12-1.17) | < 0.0001 | |
| Sex | 0.84 (0.61-1.16) | 0.28 | |
| Subgroup analysis1 | OR (95%CI) | P value | |
| GRS: < 1 (Ref)2 | - | - | |
| GRS: 1-2 | 1.39 (1.03-1.84) | 0.031 | |
| GRS: > 2 | 1.99 (1.30-3.04) | 0.002 | |
| < 10th P (Ref)3 | - | - | |
| 10th-50th P | 1.18 (0.69-2.01) | 0.548 | |
| 50th-90th P | 1.57 (0.93-2.66) | 0.089 | |
| > 90th P | 2.29 (1.25-4.21) | 0.007 | |
1
Univariate mode.
2
P trend = 0.0006.
3
P trend = 0.0008. OR: Odds ratio; CI: Confidence interval; GRS: Genetic risk score.