Table 4.
COX proportional hazard model for the cardiac death of the study cohort
| Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-value | HR | 95% CI | p-value | |
| Age | 1.066 | 1.041–1.091 | < 0.001 | 1.068 | 1.038–1.099 | < 0.001 |
| Male sex | 3.543 | 2.132–5.889 | < 0.001 | 2.100 | 1.196–3.688 | 0.01 |
| Hypertension | 1.968 | 1.082–3.582 | 0.027 | – | – | – |
| Diabetes | 1.429 | 0.835–2.444 | 0.193 | – | – | – |
| Smoking | 0.684 | 0.288–1.011 | 0.099 | – | – | – |
| Prior Stroke | 1.865 | 1.007–3.453 | 0.047 | 1.989 | 1.124–3.523 | 0.018 |
| Hyperlipdemia | 0.177 | 0.024–1.276 | 0.086 | – | – | – |
| Known kidney dysfunction | 1.764 | 1.035–3.007 | 0.037 | – | – | – |
| Prior MI | 1.345 | 0.328–5.519 | 0.681 | – | – | – |
| Pre-procedural SBP | 0.992 | 0.975–1.001 | 0.081 | – | – | – |
| Pre-procedural HR | 1.019 | 1.003–1.035 | 0.017 | – | – | – |
| LVEF, per % increased | 0.949 | 0.909–0.991 | 0.017 | 0.911 | 0.871–0.954 | < 0.001 |
| TG, per mmol/L increased | 0.889 | 0.679–1.165 | 0.394 | – | – | – |
| TCh, per mmol/L increased | 0.811 | 0.623–1.055 | 0.118 | – | – | – |
| LDL-C, per mmol/L increased | 0.74 | 0.518–1.057 | 0.098 | |||
| HDL-C, per mmol/L increased | 1.075 | 0.572–2.020 | 0.823 | – | – | – |
| Multivessel lesions | 1.954 | 1.191–3.208 | 0.008 | – | – | – |
| Time of symptom-wire, per hour increased | 1.011 | 0.999–1.023 | 0.081 | – | – | – |
| IABP utility | 2.004 | 0.951–4.224 | 0.068 | – | – | – |
| Shock index (per 0.1 increased) | 1.2 | 1.079–1.334 | 0.001 | – | – | – |
| Anterior MI | 0.795 | 0.479–1.319 | 0.374 | – | – | – |
| Onset stage of CS | ||||||
| Non- CS (reference) | 1 | – | – | 1 | – | – |
| CS on admission | 3.345 | 1.496–7.479 | 0.003 | 2.739 | 1.210–6.204 | 0.016 |
| developed CS | 2.346 | 1.252–4.395 | 0.008 | 2.233 | 1.164–4.286 | 0.016 |
| Killips Classification | ||||||
| Killips = 1(reference) | 1 | – | – | – | – | – |
| Killips = 2 | 2.737 | 1.502–4.988 | 0.001 | – | – | – |
| Killips = 3 | 3.84 | 1.694–8.700 | 0.007 | – | – | – |
| Killips = 4 | 4.13 | 1.460–11.681 | 0.001 | – | – | – |
| post-PCI TIMI flow of IRA | ||||||
| 3(reference) | 1 | – | – | – | – | – |
| 2 | 4.403 | 1.071–18.098 | 0.04 | – | – | – |
| 1 | 6.488 | 1.191–27.228 | 0.035 | – | – | – |
MACE Major adverse cardiac events, CS Cardiogenic shock, SBP Stytolic blood pressure, HR Heart rate, bpm beats per minute, LVEF Left ventricular ejection fraction, TG Triglyceride, LDL-C Low density lipoprotein cholesterol, HDL-C High density lipoprotein cholesterol, TC Total cholesterol, IABP Intra-aortic balloon pump, MI Myocardial infarction, TIMI Thrombolysis in myocardial infarction, IRA Infarct-related artery, PCI Percutaneous coronary intervention