Table 5.
COX proportional hazard model for the MACE of the study cohort
| Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-value | HR | 95% CI | p-value | |
| Age | 1.028 | 1.016–1.040 | < 0.001 | 1.017 | 1.005–1.031 | 0.005 |
| Male sex | 1.413 | 1.010–1.882 | 0.043 | – | – | – |
| Hypertension | 1.009 | 0.760–1.340 | 0.95 | – | – | – |
| Diabetes | 1.23 | 0.912–1.660 | 0.175 | – | – | – |
| Smoking | 0.812 | 0.617–1.068 | 0.136 | – | – | – |
| Prior Stroke | 1.863 | 1.338–2.594 | < 0.001 | 1.639 | 1.146–2.344 | 0.007 |
| Hyperlipdemia | 0.909 | 0.545–1.514 | 0.713 | – | – | – |
| Known kidney dysfunction | 0.827 | 0.589–1.162 | 0.274 | – | – | – |
| Prior MI | 1.549 | 0.763–3.145 | 0.226 | – | – | – |
| Pre-procedural SBP | 0.996 | 0.990–1.002 | 0.213 | – | – | – |
| Pre-procedural HR | 1.005 | 0.997–1.013 | 0.192 | – | – | – |
| LVEF, per % increased | 0.962 | 0.940–0.984 | 0.001 | 0.978 | 0.954–0.997 | 0.044 |
| TG, per mmol/L increased | 0.892 | 0.770–1.032 | 0.124 | – | – | – |
| TCh, per mmol/L increased | 0.927 | 0.807–1.065 | 0.285 | – | – | – |
| LDL-C, per mmol/L increased | 0.989 | 0.933–1.048 | 0.700 | – | – | – |
| HDL-C, per mmol/L increased | 0.827 | 0.556–1.230 | 0.348 | – | – | – |
| Multivessel lesions | 1.444 | 1.091–1.911 | 0.01 | 1.462 | 1.098–1.947 | 0.009 |
| Time of symptom-wire, per hour increased | 1.003 | 0.994–1.013 | 0.477 | – | – | – |
| IABP utility | 1.108 | 0.665–1.847 | 0.693 | – | – | – |
| Shock index (per 0.1 increased) | 1.051 | 1.003–1.102 | 0.038 | – | – | – |
| Anterior MI | 0.739 | 0.562–0.972 | 0.031 | – | – | – |
| Onset stage of CS | ||||||
| Non- CS (reference) | 1 | – | – | 1 | – | – |
| CS on admission | 2.252 | 1.345–3.770 | 0.002 | 1.948 | 1.164–3.261 | 0.011 |
| developed CS | 1.069 | 0.711–1.608 | 0.748 | 1.082 | 0.691–1.691 | 0.73 |
| Killips Classification | ||||||
| Killips = 1(reference) | 1 | – | – | – | – | – |
| Killips = 2 | 1.34 | 0.933–1.925 | 0.113 | – | – | – |
| Killips = 3 | 1.864 | 0.914–3.801 | 0.087 | – | – | – |
| Killips = 4 | 2.389 | 1.423–4.013 | 0.001 | – | – | – |
| post-PCI TIMI flow of IRA | ||||||
| 3 (reference) | 1 | – | – | 1 | – | – |
| 2 | 2.528 | 0.938–6.812 | 0.067 | 2.604 | 0.634–10.078 | 0.181 |
| 1 | 3.38 | 0.837–13.643 | 0.087 | 3.108 | 1.130–8.026 | 0.02 |
MACE Major adverse cardiac events, CS Cardiogenic shock, SBP Stytolic blood pressure, HR Heart rate, bpm beats per minute, LVEF Left ventricular ejection fraction, TG Triglyceride, LDL-C Low density lipoprotein cholesterol, HDL-C High density lipoprotein cholesterol, TC Total cholesterol, IABP Intra-aortic balloon pump, MI Myocardial infarction, TIMI Thrombolysis in myocardial infarction, IRA Infarct-related artery, PCI Percutaneous coronary intervention