Table 2.

Analysis of factors associated with carbapenem-non-susceptibility in invasive Acinetobacter spp. isolates

	Univariable analysis			Multivariable analysis
	OR	(95% CI)	p-value	OR	(95% CI)	p-value
Year of sampling
2013–2017	1.02	(0.88–1.18)	0.844	1.03	(0.94–1.13)	0.571
European region
Northern	1	–	–	1	–	–
Western	2.37	(0.98–5.74)	0.056	2.66	(1.04–6.82)	0.041
Southern	109	(47.2–250)	< 0.001	83.76	(33.79–207.66)	< 0.001
Eastern	88.4	(38.3–204)	< 0.001	75.87	(31.23–184.32)	< 0.001
Patient gender
Female	1	–	–	1	–	–
Male	1.54	(1.36–1.73)	< 0.001	1.17	(1.03–1.33)	0.013
Patient age
< 1 years	0.36	(0.16–0.82)	0.014	0.24	(0.10–0.59)	0.002
1–19 years	0.20	(0.12–0.32)	< 0.001	0.28	(0.16–0.49)	< 0.001
20–39 years	1	–	–	1	–	–
40–59 years	1.36	(1.01–1.84)	0.044	1.25	(0.88–1.77)	0.217
60–79 years	1.20	(0.91–1.58)	0.195	1.21	(0.92–1.56)	0.178
80+ years	0.78	(0.58–1.07)	0.123	1.16	(0.85–1.59)	0.352
Specimen (sampling site)
Blood	1	–	–	1	–	–
CSF	1.42	(1.00–2.01)	0.052	0.78	(0.45–1.35)	0.373
Hospital unit type
Internal medicine	1	–	–	1	–	–
Intensive care	6.62	(5.26–8.33)	< 0.001	3.79	(2.94–4.88)	< 0.001
Oncology	0.49	(0.32–0.74)	< 0.001	0.61	(0.43–0.87)	0.006
Surgery	1.47	(1.16–1.88)	0.002	1.17	(0.85–1.60)	0.341
Other	0.64	(0.47–0.85)	0.003	0.81	(0.62–1.06)	0.13
Season
Warm months	0.83	(0.73–0.94)	0.003	0.86	(0.73–1.02)	0.087
Cold months	1	–	–	1	–	–

Abbreviations: 95% CI 95% confidence interval, CSF Cerebrospinal fluid, OR Odds ratio