Table 2.
Table of demographic data for study participants
| Demographic characteristics | Overall | Control group | Intervention group |
|---|---|---|---|
| (n = 26) | (n = 13) | (n = 13) | |
| Age (y), mean (SD) | 45.8 (11.1) | 45.6 (11.6) | 45.9 (11.2) |
| Gender (male/female, n), (%) | 13/13, (54) | 7/6, (54) | 6/7, (46) |
| Alcohol intake (units per week), mean (SD) | 5.7 (6.7) | 6.9 (8.0) | 4.6 (5.0) |
| Smoking (cigarettes per day), mean (SD) | 2.0 (5.1) | 0.7 (2.8) | 3.3 (6.6) |
| Caffeine (yes/ no, n), (%) | 23/26 (88%) | 13/0 (100%) | 10/3 (77%) |
| Handedess (R/ L, n) (%) | 22/4, (85%) | 11/2, (85%) | 11/2, (85%) |
| Years in Education (y), mean (SD) | 14.9 (4.9) | 14.4 (5.4) | 15.4 (4.6) |
| CAG Repeat Length | 43.2 (2.4) | 43.1 (2.2) | 43.3 (2.7) |
| Symbol Digit Modality (SDMT) Scorea, mean (SD) | 39.8 (16.2) | 44.4 (17.3) | 35.5 (14.5) |
| Total Functional Capacity (TFC) Scorea, mean (SD) | 11.0 (2.9) | 12.0 (1.8) | 10.2 (3.4) |
| Outcome Clinical Characteristics | |||
| Categorical verbal fluency score, mean (SD) | 18.1 (6.2) | 19.4 (6.9) | 16.8 (5.3) |
| HDProTriad Total Scorea, mean (SD) | 5.5 (1.4) | 4.6 (0.9) | 6.3 (1.4) |
| HDPro Triad Total Motor Scoreb, mean (SD) | 1.4 (0.6) | 1.1 (0.2) | 1.7 (0.7) |
| HDPro Triad Total Cognitive Scoreb, mean (SD) | 2.1 (0.8) | 1.7 (0.5) | 2.4 (0.8) |
| HDPro Triad Emotional Scoreb, mean (SD) | 2.0 (0.6) | 1.7 (0.5) | 2.3 (0.6) |
aParticipant data for CAG repeat length, symbol digit modality test and total functional capacity score are taken from the most recent ENROLL-HD visit of the participant
bThe HDProTriad questionnaire was developed for use in HD and measures motor function, cognition and emotion. Higher scores indicate a greater degree of impairment, and a score of one indicates normal function