Table 1.
The incidence and its trends of leukemia, by sex, age, type, and region, between 1990 and 2017
| 1990 | 2017 | 1990-2017 | |||
|---|---|---|---|---|---|
| Case number () | ASIR (/105) | Case number () | ASIR (/105) | EAPC (95% CI) | |
| Overall | 354.5 | 7.42 | 518.5 | 6.76 | − 0.43 (− 0.48, − 0.38) |
| Sex | |||||
| Male | 191.3 | 8.48 | 295.4 | 8.09 | − 0.26 (− 0.32, − 0.21) |
| Female | 163.1 | 6.57 | 223.1 | 5.62 | − 0.65 (− 0.70, − 0.60) |
| Age (years)a | |||||
| Under 5 | 54.4 | 8.44 | 52.9 | 7.78 | − 0.12 (− 0.20, − 0.05) |
| 5–14 | 50.6 | 4.51 | 45.5 | 3.51 | − 1.18 (− 1.38, − 0.98) |
| 15–49 | 102.4 | 3.74 | 123.1 | 3.15 | − 0.89 (− 1.00, − 0.77) |
| 50–69 | 80.0 | 11.64 | 149.7 | 11.36 | − 0.24 (− 0.33, − 0.15) |
| 70+ | 67.0 | 32.96 | 147.3 | 34.03 | 0.11 (0.08, 0.14) |
| Types | |||||
| ALL | 49.1 | 0.89 | 64.2 | 0.85 | − 0.08 (− 0.15, − 0.02) |
| CLL | 38.0 | 0.99 | 90.6 | 1.15 | 0.46 (0.40, 0.52) |
| AML | 63.8 | 1.35 | 119.6 | 1.54 | 0.56 (0.49, 0.62) |
| CML | 31.8 | 0.75 | 34.2 | 0.43 | − 2.40 (− 2.53, − 2.26) |
| Others | 171.8 | 3.43 | 209.9 | 2.78 | − 0.93 (− 1.02, − 0.84) |
| SDI region | |||||
| High | 106.6 | 9.10 | 150.8 | 7.73 | − 0.67 (− 0.74, − 0.60) |
| High-middle | 80.4 | 7.59 | 123.7 | 8.68 | 0.56 (0.50, 0.63) |
| Middle | 93.2 | 6.57 | 131.9 | 6.47 | − 0.19 (− 0.34, − 0.04) |
| Low-middle | 44.4 | 4.87 | 66.8 | 4.54 | − 0.34 (− 0.40, − 0.28) |
| Low | 27.9 | 4.68 | 42.6 | 4.14 | − 0.55 (− 0.59, − 0.50) |
| GBD region | |||||
| Andean Latin America | 2.1 | 6.00 | 3.5 | 5.97 | 0.12 (− 0.01, 0.26) |
| Australasia | 3.0 | 13.38 | 4.2 | 9.62 | − 1.65 (− 1.92, − 1.38) |
| Caribbean | 2.1 | 6.72 | 2.8 | 5.82 | − 0.59 (− 0.68, − 0.50) |
| Central Asia | 3.5 | 5.17 | 4.0 | 4.74 | − 0.20 (− 0.31, − 0.08) |
| Central Europe | 9.1 | 6.71 | 11.1 | 6.37 | 0.02 (− 0.12, 0.17) |
| Central Latin America | 9.1 | 6.39 | 14.5 | 5.89 | − 0.32 (− 0.38, − 0.27) |
| Central sub-Saharan Africa | 1.8 | 4.07 | 3.4 | 3.87 | − 0.24 (− 0.27, − 0.20) |
| East Asia | 102.3 | 8.49 | 147.7 | 10.54 | 0.83 (0.63, 1.02) |
| Eastern Europe | 17.1 | 7.00 | 19.7 | 6.91 | 0.06 (− 0.08, 0.21) |
| Eastern sub-Saharan Africa | 7.2 | 4.66 | 13.3 | 4.48 | − 0.29 (− 0.38, − 0.20) |
| High-income Asia Pacific | 11.3 | 6.22 | 17.8 | 5.27 | − 0.47 (− 0.57, − 0.38) |
| High-income North America | 27.4 | 8.17 | 39.6 | 7.17 | − 0.61 (− 0.78, − 0.43) |
| North Africa and Middle East | 19.3 | 7.08 | 32.3 | 6.37 | − 0.24 (− 0.31, − 0.17) |
| Oceania | 0.3 | 6.61 | 0.6 | 6.34 | − 0.07 (− 0.11, − 0.03) |
| South Asia | 40.7 | 4.24 | 62.0 | 3.99 | − 0.30 (− 0.39, − 0.22) |
| Southeast Asia | 24.2 | 6.26 | 38.9 | 6.37 | 0.07 (− 0.04, 0.19) |
| Southern Latin America | 3.0 | 6.25 | 3.9 | 5.29 | − 0.68 (− 0.75, − 0.61) |
| Southern sub-Saharan Africa | 1.6 | 4.36 | 2.5 | 4.10 | − 0.30 (− 0.69, 0.08) |
| Tropical Latin America | 7.2 | 5.50 | 10.2 | 4.65 | − 0.58 (− 0.67, − 0.49) |
| Western Europe | 56.8 | 10.62 | 75.7 | 8.86 | − 0.76 (− 0.83, − 0.69) |
| Western sub-Saharan Africa | 5.3 | 3.44 | 10.8 | 3.40 | − 0.14 (− 0.23, − 0.05) |
ASIR age-standardized incidence rate, EAPC estimated average percentage change, SDI socio-demographic index, ALL acute lymphoblastic leukemia, CLL chronic lymphoblastic leukemia, AML acute myeloid leukemia, CML chronic myeloid leukemia
aThe incidence rates for each age group were crude incidence rather than the age-standardized incidence