Table 1.

Analysis of differences in expression levels of inflammasome related molecules in HNSCC by Oncomine Database

	Head–neck carcinoma vs. normal			Head–neck carcinoma vs. buccal mucosa			Head–neck carcinoma vs. normal
	TCGA head–neck database (n = 290)			Ginos head–neck database (n = 54)			Cromer head–neck database (n = 38)
	Fold change	P-value	t-test	Fold change	P-value	t-test	Fold change	P-value	t-test
IFI16	1.048	1.71E−11	6.889	3.115	9.22E−15	13.011	1.435	0.17	1.117
AIM2	1.048	1.71E−11	6.882	5.674	6.51E−14	11.201	2.028	0.001	3.912
NLRP1	− 1.035	1	− 4.674	1.674	0.037	1.878	1.089	0.428	0.192
NLRP3	1.053	3.73E−12	7.133	1.4551	0.035	1.879	1.555	0.192	0.976
NLRC4	1.033	2.02E−08	5.633
NLRC5	1.001	0.443	0.144
NLRP6	− 1.064	1	− 7.355
NLRP12	− 1.017	0.994	− 2.53
NOD1	1.08	1.64E−19	9.62	2.322	1.12E−04	5.034
NOD2	− 1.005	0.747	− 0.664	− 1.72	1	− 3.866
CASP1	− 1.079	1	− 6.227	1.445	4.26E−04	3.548	1.325	0.215	0.869
IL1B	1.028	2.40E−06	4.661	2.801	1.77E−08	6.605	4.908	0.002	5.574