Table 8.

Histopathological assessment of dietary agrimos® supplementation on E. coli challenged broiler chicken ((n = 10)

Lesions	Infected group						Agrimos non-infected group						Agrimos infected group
	At 15 days			At 35 days			At 15 days			At 35 days			At 15 days			At 35 days
	B	T	S	B	T	S	B	T	S	B	T	S	B	T	S	B	T	S
Sub capsular heterophilic aggregation	–		Normal	–		Normal	Normal	Normal	Normal	Normal	Normal	Normal	–	Normal	Normal	–		Normal
Sub and interstitial edema	–			–									+			+
Interstitial hemorrhages	–			–									–			+
Interstitial connective tissue proliferation	–			–									–			–
Epithelial folding and lobulation	+			–									–			–
Epithelial hyperplasia	+			+									+			+
Epithelial degeneration and/or necrosis	+			+									–			+
Reduction in size and numbers of follicles	–			–									–			–
Follicular atrophy or cortical atrophy	–			–	+								–			+	+
Follicular cyst and necrosis	–			–									–			+
Lymphocytic depletion	–			–									–			+
Appearance of holes in medulla	–	+		–	++								–			–
Reticular cells proliferation	–			–									–			–
Vasculitis	–			–									–			–
Cortical necrosis	–			–									–			–
Apoptotic bodies and/or karyorhexis	–	+		–									–			–
Hyalinization and thrombosis of blood vessels	–			–									–			–

+++ Sever ++ Moderate + Mild B = Bursa T = Thymus S=Spleen