Table 4.
Changes in cerebral glucose metabolism after 4–6 months of STN DBS in Parkinson's Disease: Voxel-wise Comparison of Pre-Operative.to On STN DBS.
| Left Hemisphere | Decreases in Metabolism | Right Hemisphere | ||||||
|---|---|---|---|---|---|---|---|---|
| X (mm) | Y (mm) | Z (mm) | Z-Score | Structure | X (mm) | Y (mm) | Z (mm) | Z-Score |
| −3 | 2 | 1 | 3.19 | Caudate (Head) | ||||
| −9 | −1 | 15 | 3.32 | Caudate (Body) | 12 | −1 | 19 | 4.86 |
| Thalamus (Ventral Anterior Nucleus) | 16 | −4 | 10 | 3.32 | ||||
| −12 | −11 | −2 | 4.19 | Subthalamic Nucleus | 16 | −12 | −6 | 3.06 |
| −25 | −20 | −5 | 3.11 | Lateral Globus Pallidus | ||||
| Putamen | 23 | 2 | 19 | 3.37 | ||||
| Left Hemisphere | Increase in Metabolism | Right Hemisphere | ||||||
| X (mm) | Y (mm) | Z (mm) | Z-Score | Structure | X (mm) | Y (mm) | Z (mm) | Z-Score |
| −42 | −29 | 19 | 2.93 | Insula (BA 13) | ||||
| −59 | −46 | 17 | 4.42 | Superior Temporal Gyrus (BA 22/38) | 33 | 15 | −33 | 3.05 |
| Parahippocampal Gyrus (BA 36) | 32 | −32 | −14 | 3.20 | ||||
| −17 | −80 | 34 | 3.79 | Precuneus (BA 7/31) | 13 | −58 | 22 | 3.56 |
| −55 | −43 | 24 | 3.73 | Inferior Parietal Lobule (BA 40) | ||||
| −20 | −81 | −11 | 3.40 | Fusiform Gyrus (BA 37) | 28 | −93 | −11 | 3.56 |
| −16 | −59 | −11 | 4.10 | Cerebellum (Culmen) | 32 | −33 | −20 | 2.89 |
| −27 | −65 | −17 | 2.84 | Cerebellum (Declive) | 23 | −71 | −15 | 4.02 |
Within-subject comparisons are reported that are significant at a cluster-level p≤0.001 (FDR corrected) and peak voxel-value of p≤0.001 (uncorrected).