Table 2.

Subgroup analyses for Scr, BUN, and UAER.

Outcome	Stage of DN	n	MD/SMD(95% CI)	I2(%)	Z	P
Scr	stage III	4	–0.97 (–5.32,3.38)	44	0.44	0.66
	stage III-IV	3	–21.31 (–23.38, –19.25)	0	20.21	<0.00001
BUN	stage III	2	–0.46 (–0.90, –0.01)	0	2.01	0.04
	stage III-IV	3	–1.29 (–1.90, –0.68)	67	4.16	<0.0001
UAER	stage III	5	–1.96 (–3.09, –0.83)	95	3.40	0.0007
	stage III-IV	1	–1.34 (–1.75, –0.93)	Not applicable	6.45	<0.00001

Scr, serum creatinine; BUN, blood urea nitrogen; UAER, urinary albumin excretion rate.