Table 2.
Partial correlations of fatty acids with symptom and functioning scores in 285 participants of the Neurapro-E study.
| BPRS | BPRS psy | SANS | MADRS | YMRS | SOFAS | GF-S | GF-R | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| adj. R | p-value | adj. R | p-value | adj. R | p-value | adj. R | p-value | adj. R | p-value | adj. R | p-value | adj. R | p-value | adj. R | p-value | |
| 16:0 | -0.111 | 0.06 | -0.011 | 0.86 | -0.210 | <0.001 | -0.082 | 0.16 | 0.009 | 0.86 | 0.104 | 0.08 | 0.105 | 0.08 | 0.072 | 0.23 |
| 17:0 | -0.015 | 0.79 | 0.029 | 0.63 | -0.084 | 0.16 | -0.011 | 0.85 | -0.006 | 0.91 | 0.034 | 0.57 | 0.085 | 0.16 | 0.136 | 0.02 |
| 18:0 | -0.029 | 0.62 | -0.019 | 0.76 | 0.053 | 0.37 | 0.039 | 0.50 | -0.055 | 0.35 | -0.129 | 0.03 | -0.113 | 0.06 | -0.112 | 0.06 |
| 18:1* | -0.119 | 0.04 | -0.008 | 0.90 | -0.191 | 0.001 | -0.123 | 0.03 | -0.140 | 0.02 | 0.109 | 0.06 | 0.065 | 0.28 | 0.121 | 0.04 |
| 18:2n-6 | -0.344 | <0.0001 | -0.119 | 0.04 | -0.328 | <0.0001 | -0.264 | <0.0001 | -0.324 | <0.0001 | 0.033 | 0.57 | 0.146 | 0.01 | 0.047 | 0.44 |
| 20:3# | -0.175 | 0.003 | -0.105 | 0.08 | -0.202 | <0.001 | -0.192 | 0.001 | -0.184 | 0.002 | 0.102 | 0.08 | 0.153 | 0.01 | 0.150 | 0.01 |
| 20:4n-6 | -0.162 | 0.006 | -0.075 | 0.21 | 0.016 | 0.78 | -0.122 | 0.03 | -0.280 | <0.0001 | -0.016 | 0.78 | 0.016 | 0.79 | -0.044 | 0.47 |
| 20:5n-3 | 0.005 | 0.92 | -0.069 | 0.25 | 0.099 | 0.09 | -0.039 | 0.50 | -0.128 | 0.03 | 0.048 | 0.42 | 0.027 | 0.65 | 0.022 | 0.72 |
| 22:4n-6 | -0.017 | 0.77 | -0.065 | 0.28 | 0.109 | 0.07 | -0.053 | 0.36 | -0.080 | 0.18 | -0.047 | 0.43 | -0.071 | 0.24 | -0.129 | 0.03 |
| 22:5^ | 0.015 | 0.80 | 0.040 | 0.50 | 0.113 | 0.06 | 0.082 | 0.16 | 0.144 | 0.02 | -0.002 | 0.97 | -0.067 | 0.27 | -0.116 | 0.05 |
| 22:6n-3 | -0.198 | <0.001 | -0.166 | 0.006 | -0.081 | 0.17 | -0.191 | 0.001 | -0.234 | <0.0001 | 0.026 | 0.65 | -0.007 | 0.90 | -0.053 | 0.38 |
| 24:0 | 0.389 | <0.001 | 0.099 | 0.09 | 0.289 | <0.0001 | 0.307 | <0.0001 | 0.375 | <0.0001 | -0.074 | 0.21 | -0.098 | 0.10 | -0.005 | 0.93 |
| 24:1n-9 | 0.365 | <0.001 | 0.157 | 0.009 | 0.293 | <0.0001 | 0.307 | <0.0001 | 0.377 | <0.0001 | -0.074 | 0.21 | -0.115 | 0.05 | -0.047 | 0.44 |
| n-3 index† | -0.176 | 0.003 | -0.160 | 0.008 | -0.057 | 0.34 | -0.177 | 0.002 | -0.230 | <0.0001 | 0.031 | 0.59 | -0.002 | 0.97 | -0.044 | 0.47 |
| n-6/3 ratio& | 0.153 | 0.01 | 0.147 | 0.01 | 0.093 | 0.12 | 0.169 | 0.005 | 0.118 | 0.05 | -0.083 | 0.16 | -0.021 | 0.73 | 0.035 | 0.56 |
* 18:1 could be 18:1n-7 or 18:1n-9, or a combination of both.
# 20:3 could be 20:3n-3, 20:3n-6 or 20:3n-9, or a combination of all 3 isomers.
^ 22:5 could be 22:5n-3 or 22:5n-6, or a combination of both.
†The n-3 index is calculated as the amount of EPA and DHA expressed as the percent of total fatty acids.
&The n-6/3 ratio is calculated as AA/(EPA + DHA).
Bold numbers indicate statistical significance.