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. 2020 May 28;4:11–43. doi: 10.5414/ALX02104E

Box 13. Important information when taking a patient history [79].

- Which medications were used prior to and at the time of the reaction (create a timeline if necessary)? Which diseases were already present at that time and were responsible for the use of a BLA?
- Precise chronology:
  - The duration of medication use
  - The time interval between the last use of the medication and the onset of symptoms
  - Duration of the reaction
  - Time period to allergy consultation or testing
- Symptoms of the BLA-related reaction (both subjective and objective symptoms) and which organ systems were involved in chronological order of occurrence, as well as laboratory findings and possible treatment interventions.
- Possible augmentation factors, such as infectious diseases and physical exertion, among others.
- Known drug hypersensitivity and other known allergies.
- Previous use and tolerance of BLA.
- General patient history: age, sex, atopy history, other disorders, and current drug use.