Table 9. Intravenous penicillin desensitization protocol using an infusion pump, dose escalation every 15 min [143].
Number | Penicillin (mg/mL) | Flow rate (mL/h) | Dose (mg) | Cumulative dose |
---|---|---|---|---|
1 | 0.01 | 6 | 0.015 | 0.015 |
2 | 0.01 | 12 | 0.03 | 0.045 |
3 | 0.01 | 24 | 0.06 | 0.105 |
4 | 0.1 | 50 | 0.125 | 0.23 |
5 | 0.1 | 10 | 0.25 | 0.48 |
6 | 0.1 | 20 | 0.5 | 1 |
7 | 0.1 | 40 | 1 | 2 |
8 | 0.1 | 80 | 2 | 4 |
9 | 0.1 | 160 | 4 | 8 |
10 | 10 | 3 | 7.5 | 15 |
11 | 10 | 6 | 15 | 30 |
12 | 10 | 12 | 30 | 60 |
13 | 10 | 25 | 62.5 | 123 |
14 | 10 | 50 | 125 | 250 |
15 | 10 | 100 | 250 | 500 |
16 | 10 | 200 | 500 | 1,000 |