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. 2020 Jun 12;7:270. doi: 10.3389/fmed.2020.00270

Figure 3.

Figure 3

Localisation and quantification of placental (A) E-selectin; (B) P-selectin and (C) L-selectin in placenta from normotensive controls (NC (A1, B1, & C1); n = 17) and pre-eclampsia (PE (A2, B2, & C2); n = 17). Negative controls for each selectins are shown in A3, B3, & C3 respectively. In photomicrographs, positive cells appear in brown; magnification x400. Scale bars represent 100 μm. Protein expression was localized to the syncytiotrophoblast layer (black arrows) and some fetal vessels (red arrows). (D) E-selectin; (E) P-selectin and (F) L-selectin expression in placenta, when sub-grouped by NC, early-onset PE (diagnosis ≤ 34 weeks gestation; n = 6) and late-onset PE (>34 weeks gestation; n = 11). Data in all box plots are presented as median [interquartile ranges]; *P < 0.05; **P < 0.001.