A-F) WT (black bars) and SP-A−/− (white bars) mice were injected with either an IL-6 inhibitor (or vehicle control) 2 hrs prior to a one time airway challenge with IL-13. Twenty-four hours post challenge A) total cells in the BAL which consisted of B) macrophages (Macs), C) neutrophils (PMNs), D) eosinophils (Eos) were examined. E) Muc5AC gene expression was examined by RT-PCR in lung tissue. F) KC, and G) Eotaxin levels were examined by ELISA. n=9,9/per group, *p<0.05, **p<0.01, ***p<0.001.