. 2020 Jun 12;8:628. doi: 10.3389/fbioe.2020.00628

TABLE 2.

Microporous zeolites as drug delivery systems for antibacterial application.

Name	Antibacterial drug	Pathogenic bacteria	Antibacterial activity	References
Zeolite X	Ag⁺	S. aureus	ZOI: 11–12 mm	Chen S. et al., 2017
	Ag⁺	E. coli C. albicans	N/A	Tosheva et al., 2017
Zeolite Y	Au NPs	E. coli S. typhi	Antibacterial efficiency = 90–95%	Lima et al., 2013
	(0.05 M)Ag⁺/(0.025 M)Zn²⁺	E. coli B. subtilis C. albicans S. cerevisiae	E. coli: MIC = 0.10 mg/mL B. subtilis: MIC = 0.10 mg/mL C. albicans: MIC = 0.30 mg/mL S. cerevisiae: MIC = 0.30 mg/mL	Ferreira et al., 2016
EMT	Ag⁺/Ag NPs	E. coli	Sterilizing time < 6 min	Dong et al., 2014
	Ag⁺	S. mutans S. gordonii S. sanguinis	The biofilm CFU count were reduced by two orders of magnitude at most	Li W. et al., 2020
ZSM-5	Gentamicin	S. epidermidis	Antibacterial efficiency = 94.32%	Guo et al., 2014
Zeolite β	Ag⁺	E. coli C. albicans	E. coli: Sterilizing time < 7 min N/A	Tosheva et al., 2017
	Ag⁺	E. coli	Sterilizing time = 1 h	Saint-Cricq et al., 2012
Zeolite A	Cu²⁺/Cu₂O	E. coli	Cu²⁺: antibacterial efficiency = 98.15% Cu₂O: antibacterial efficiency = 96.19%	Du et al., 2017
	TiO₂/ZnO	E. coli S. aureus P. fluorescens L. monocytogenes	E. coli: MIC = 1 ± 0.01 mg/mL; MBC = 2 ± 0.01 mg/mL S. aureus: MIC = 2 ± 0.01 mg/mL; MBC = 3 ± 0.01 mg/mL P. fluorescens: MIC = 1 ± 0.01 mg/mL; MBC = 2 ± 0.01 mg/mL L. monocytogenes: MIC = 2 ± 0.01 mg/mL; MBC = 3 ± 0.01 mg/mL	Azizi-Lalabadi et al., 2019
	Ag⁺	S. milleri E. faecalis S. aureus	The bactericidal effect is dose dependent	Çınar et al.,2009
	Ag⁺	E. faecalis S. aureus C. albicans E. coli P. aeruginosa P. gingivalis A. israelii P. intermedia	E. faecalis: ZOI: 7.06 ± 0.36 mm S. aureus: ZOI: 7.54 ± 0.36 mm C. albican: ZOI: 10.73 ± 0.54 mm E. coli: ZOI: 9.44 ± 0.18 mm P. aeruginosa: ZOI: 11.00 ± 0.34 mm P. gingivalis: ZOI: 8.84 ± 0.88 mm A. israelii: ZOI: 0.00 ± 0.00 mm P. intermedia: ZOI: 0.00 ± 0.00 mm	Odabaş et al., 2011

Abbreviations: Ag NPs, silver nanoparticles; Ag⁺, silver ion; A. israelii, Actinomyces israelii; Au NPs, gold nanoparticles; B. subtilis, Bacillus subtilis; C. albicans, Candida albicans; CFU, colony forming unit; Cu²⁺, copper ions; Cu₂O, cuprous oxide; E. coli, Escherichia coli; E. faecalis, Enterococcus faecalis; L. monocytogenes, Listeria monocytogenes; MBC, minimal bactericidal concentration; MIC, minimal inhibition concentration; P. aeruginosa, Pseudomonas aeruginosa; P. fluorescens, Pseudomonas fluorescens; P. intermedia, Prevotella intermedia; P. gingivalis, Porphyromonas gingivalis; S. aureus, Staphylococcus aureus; S. cerevisiae, Saccharomyces cerevisiae; S. epidermidis, Staphylococcus epidermidis; S. gordonii, Streptococcus gordonii; S. milleri, Streptococcus milleri; S. mutans, Streptococcus mutans; S. sanguinis, Streptococcus sanguinis; S. typhi, Salmonella typhi; TiO₂, cerium dioxide; Zn²⁺, zinc ion; ZnO, zinc oxide; ZOI, zone of inhibition.