Skip to main content
. Author manuscript; available in PMC: 2020 Sep 25.
Published in final edited form as: Sci Transl Med. 2020 Mar 25;12(536):eaay0271. doi: 10.1126/scitranslmed.aay0271

Fig. 4. Hypoxia signaling inhibitors reduce FSHD-related biomarkers in patient primary myotubes.

Fig. 4.

Transcript quantification of FSHD biomarkers MBD3L5, ZSCAN4, and TRIM43 from four patient donor muscle biopsies (12A, 16A, 17A, 18A from UMMS Wellstone cohort) with or without compound treatment for five days were normalized and summarized (original values of each line in fig. S7. Data are plotted as mean ± SEM. Statistical analysis: Two-way ANOVA and multiple comparisons test were performed and all treatment groups were significantly different from untreated control (P<0.0001).