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. 2020 Jun 12;8:337. doi: 10.3389/fcell.2020.00337

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Copyright © 2020 Khmelinskaia, Marquês, Bastos, Antunes, Bento-Oliveira, Scolari, Lobo, Malhó, Herrmann, Marinho and de Almeida.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Zym does not promote the formation of coexisting l_d/l_o liquid phases. Confocal microscopy images of GUVs of (A) DOPC/DPPC (1:1 molar ratio), (B) DOPC/DPPC/Erg (1:1:1 molar ratio), (C) DOPC/DPPC/Zym (1:1:2 molar ratio) at 23°C, labeled with Rhod-DOPE (0.2 mol%). Scale bar = 5 μm.